OrangerV1, Main, Exploration, bibRecord, 000D52

Preliminary Examination of Herbal Extracts on the Inhibition of Helicobacter Pylori

Identifieur interne : 000D52 ( Main/Exploration ); précédent : 000D51; suivant : 000D53

Preliminary Examination of Herbal Extracts on the Inhibition of Helicobacter Pylori

Auteurs : Gulcihan Guzeldag [Turquie] ; Lutfiye Kadioglu [Turquie] ; Aysun Mercimek [Turquie] ; Fatih Matyar [Turquie]

Source :

African Journal of Traditional, Complementary, and Alternative Medicines [ 0189-6016 ] ; 2013.

RBID : PMC:3957247

English descriptors

KwdEn :
- Anti-Bacterial Agents (pharmacology), Citrus, Helicobacter Infections (microbiology), Helicobacter pylori (drug effects), Laurus, Microbial Sensitivity Tests, Plant Extracts (pharmacology).
MESH :
- chemical , pharmacology : Anti-Bacterial Agents, Plant Extracts.
- drug effects : Helicobacter pylori.
- microbiology : Helicobacter Infections.
- Citrus, Laurus, Microbial Sensitivity Tests.

Abstract

Background

This work aims at describing the traditional uses, to determine the antimicrobial potential of two different extracts hexane, acetone of the leaves of Citrus unshiu, Citrus sinensis, Citrus limon, Laurus nobilis, Citrus paradisi on clinical strain of H. pylori in a bid to identify potential sources of cheap starting materials for the synthesis of new drugs. H. pylori strain was a culture collection of Hacettepe University, Turkey.

Methods

The activity was quantitatively assessed on the basis of the inhibition zone, and their activity index was also calculated along with the MIC method.

Results

All the plants demonstrated antimicrobial activity against H. pylori with zone of inhibition diameters ranging from 0 – 30 mm and minimum inhibitory concentration (MIC) values ranging from 1:512–1:4096 dilutions.

Conclusion

The results may serve as scientific validation of the ethnomedicinal uses of the Citrus unshiu, Citrus sinensis, Citrus limon, Laurus nobilis, and Citrus paradisi in the treatment of H. pylori-related infections. However, further investigations would be necessary to determine their toxicological properties, in-vivo potencies and mechanism of action against H. pylori.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957247

PubMed: 24653559
PubMed Central: 3957247

Affiliations:

Turquie

Le document en format XML

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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>This work aims at describing the traditional uses, to determine the antimicrobial potential of two different extracts hexane, acetone of the leaves of <italic>Citrus unshiu, Citrus sinensis, Citrus limon, Laurus nobilis, Citrus paradisi</italic>
 on clinical strain of <italic>H. pylori</italic>
 in a bid to identify potential sources of cheap starting materials for the synthesis of new drugs. <italic>H. pylori</italic>
 strain was a culture collection of Hacettepe University, Turkey.</p>
</sec>
<sec sec-type="methods"><title>Methods</title>
<p>The activity was quantitatively assessed on the basis of the inhibition zone, and their activity index was also calculated along with the MIC method.</p>
</sec>
<sec sec-type="results"><title>Results</title>
<p>All the plants demonstrated antimicrobial activity against <italic>H. pylori</italic>
 with zone of inhibition diameters ranging from 0 – 30 mm and minimum inhibitory concentration (MIC) values ranging from 1:512–1:4096 dilutions.</p>
</sec>
<sec sec-type="conclusions"><title>Conclusion</title>
<p>The results may serve as scientific validation of the ethnomedicinal uses of the <italic>Citrus unshiu, Citrus sinensis, Citrus limon, Laurus nobilis</italic>
, and <italic>Citrus paradisi</italic>
 in the treatment of <italic>H. pylori</italic>
-related infections. However, further investigations would be necessary to determine their toxicological properties, in-vivo potencies and mechanism of action against <italic>H. pylori</italic>
.</p>
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Preliminary Examination of Herbal Extracts on the Inhibition of Helicobacter Pylori

Preliminary Examination of Herbal Extracts on the Inhibition of Helicobacter Pylori

Source :

English descriptors

Abstract

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